• Selective androgen receptor modulators, or SARMs, were first unveiled in the late 1990s and quickly gained popularity within the weightlifting community.
  • The best SARMs for cutting can help bodybuilders lose pounds without sacrificing muscle mass and enhance their physiques.
  • Ostarine (MK-2866), Andarine (S4), Cardarine (GW-501516), and Stenabolic (SR9009) are among the leading SARMs for fat loss.

Selective androgen receptor modulators, better known as SARMs, are non-steroidal compounds that were discovered by researchers more than 25 years ago. When used properly, the best SARMs for cutting can help workout warriors lose weight while maintaining muscle mass, resulting in an enhanced physique.

However, it’s essential for fitness fanatics to rely only on the top SARMs for weight loss rather than simply selecting the first SARMs they can find. The U.S. Food and Drug Administration, which has yet to approve SARMs, has repeatedly warned those in the bodybuilding world against using certain SARMs, citing safety concerns.

So, what are the best SARMs for fat loss? In this article, we’ll break down everything you need to know about SARMs and highlight some you can consider adding to your workout routine.

What Are SARMs, and How Do They Work?

Before taking a deep dive into the best SARMs for cutting, let’s make sure you have a general understanding of what SARMs are and how they work. Because they have only been around since the late 1990s, they aren’t on everyone’s radar yet.

Selective androgen receptor modulators, or SARMs, are a class of therapeutic compounds that offer properties similar to anabolic steroids. The major difference between the two is that SARMs have reduced androgenic properties, which are known to produce male characteristics.

SARMs work by selectively binding to androgen receptors, which are proteins located within cells. More specifically, they target the ARs in the tissues situated within muscles and bones, enabling them to promote muscle growth and bone density.

Over the last two-plus decades, many people have utilized SARMs to enhance their muscle strength. Using SARMs for weight loss has also become increasingly popular. However, it’s worth noting that not all SARMs are created equal, as certain options stand out more than others by increasing lean muscle mass and burning fat more effectively overall.

Woman doing deadlifts in a gym


How Do You Take SARMs?

Those who use anabolic steroids to enjoy greater gains in the gym typically take them in the form of intramuscular injections. Thankfully, anyone who opts to incorporate SARMs into their fitness regimen will not have to worry about doing this.

More often than not, SARMs are consumed orally as capsules, but you can also get liquid and powder SARMs.

No matter how you take SARMs, follow manufacturers’ instructions to ensure they work their way into your system quickly, allowing you to reap their rewards. Experts also usually advise people to “cycle” SARMs, which involves taking them for a specific period before giving your body a break. This may prevent the possible side effects of SARMs, including liver damage and heart problems.

Additionally, some experts swear by “stacking” the best SARMs for cutting. This requires taking more than one SARM at a time to achieve multiple fitness goals simultaneously.

What Are the Benefits of SARMs?

Even though SARMs showed up on the bodybuilding scene years ago, studies are still being conducted to determine their benefits. Keep that in mind before choosing to take them.

At the same time, be aware of the potential benefits that have emerged during the ongoing SARMs studies. Here are several ways in which taking the best SARMs for cutting and weight loss might be beneficial:

  • May make muscles grow quicker
  • May jumpstart weight-loss efforts
  • May improve bone density
  • May minimize side effects associated with anabolic steroids
Man adding a plate to a barbell in a gym

What Are the Best SARMs for Cutting and Fat Loss?

Approximately a dozen SARMs are used by bodybuilders and others seeking to build lean muscle while reducing unwanted fat. Selecting the best SARMs for fat loss and cutting is crucial if you plan to use them to transform your physique with a power rack or Smith machine. Check out a few of the leading options.

Ostarine (MK-2866)

Ostarine has turned into one of the most popular SARMs among bodybuilders and athletes. It’s capable of enhancing fat loss and preserving muscle mass without subjecting users to as many side effects as other SARMs. It targets the androgen receptors in muscles and bones with precision, serving as an essential part of the cutting cycle.

Andarine (S4)

Andarine is another dual-purpose SARM for those seeking to lose weight while hardening their muscles and enhancing their density. Notably, it can bind to the androgen receptors found within adipose tissues, commonly known as fat, to aid in weight-loss efforts.

Cardarine (GW-501516)

Cardarine isn’t one of the traditional SARMs, but it behaves like one once it enters the body. It can increase a person’s endurance, promoting fat loss. It activates PPARδ, a receptor that encourages the body to utilize fat as a source of energy, making it one of the top SARMs for weight loss.

Stenabolic (SR9009)

Like Cardarine, Stenabolic is not a conventional SARM option. However, it still deserves to be categorized alongside the best SARMs for cutting since it works by altering a person’s metabolic functions and circadian rhythms to improve their endurance and increase their fat-burning abilities.

Important Notes Before Using SARMs for Cutting

  • SARMs are not approved by the FDA for human consumption

  • Potential risks include hormonal suppression, liver strain, and unknown long-term effects

  • Buy only from reputable sources and do post-cycle therapy (PCT) if needed

  • Diet and training matter more—SARMs aren't magic

Major Fitness Disclaimer

Major Fitness does not promote any weight loss protocol that does not involve guidance and monitoring from a physician or a certified health expert. Always consult your doctor or licensed health expert before taking any weight loss supplements, and always follow their suggestions for healthy weight loss protocols. SARMs are a sports-specific type of weight loss supplement and are not suitable for everyone. This article is only meant to inform readers about the specific sport applications of SARMs. This article is not meant as medical advice or meant to replace the input of your medical provider. We encourage everyone to have open and honest conversations with their health providers about their health goals and what steps they can take to reach them in a healthy, sustainable way. 

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